NCCN指南已经将CPT-11联合铂类列为晚期非小细胞肺癌一线治疗方案。本项研究结果显示,CPT-11+DDP治疗晚期NSCLC疗效确切,用药剂量患者尚可耐受,对于CPT-11所导致的骨髓抑制及腹泻反应及早进行干预,但对于晚期复治及多程治疗后患者及KPS评分<70分患者,如何使用CPT-11值得进一步深入研究。
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