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您现在的位置: 医学全在线 > 医学论文 > 论文投稿 > 正文:医学论文范文:2007-2009年我院3种非发酵革兰阴性杆菌药物敏感性调查
    

医学论文范文:2007-2009年我院3种非发酵革兰阴性杆菌药物敏感性调查

来源:本站原创 更新:2013-9-16 论文投稿平台

医学论文范文:2007-2009年我院3种非发酵革兰阴性杆菌药物敏感性调查

【摘要】 目的:了解鲍曼不动杆菌、铜绿假单胞菌、嗜麦芽窄食单胞菌对常用抗菌药物的耐药性。方法:KB法对分离菌株进行抗菌药物药敏试验。结果:分别分离铜绿假单胞菌、鲍曼不动杆菌、嗜麦芽窄食单胞菌745、367和25株。鲍曼不动杆菌耐药率达90%(头孢哌酮/舒巴坦例外,18%)。铜绿假单胞菌对复方新诺明、头孢噻肟庆大霉素哌拉西林耐药率80%。嗜麦芽窄食单胞菌分离率不高,对环丙沙星头孢哌酮/舒巴坦、复方新诺明耐药率小于35%,对头孢噻肟、氨曲南、哌拉西林耐药率均超过80%。多重耐药菌株数分离率呈上升趋势,2009年58.54%菌株对5种抗生素均耐药。结论:3种非发酵糖革兰阴性杆菌耐药性严重,临床应根据药敏结果合理使用抗生素。

【关键词】 院内感染;非发酵糖革兰阴性杆菌;多重耐药

Drug Susceptibility of Three Nonfermentation Gram Negative Bacilli in 2007-2009 HOU Lingli1,2,TAO Jianshu1,ZHANG Jicai2,LV Jun2,YANG Hongwei2^,FENG Jing2 (Department of Clinical Laboratory,1Guiyang Medical College,Guiyang,Guizhou 550000;2Taihe Hospital,Yunyang Medical College,Shiyan,Hubei 442000,China)

Abstract: Objective To analyze the drug susceptibility of Acinetobacter baumannii,Pseudomonas aeruginosa and Stenotrophomonas maltophilia to clinical common antibacterials.Methods The drug susceptibility of isolated strains were determined with KB method.Results A total of 745,367 and 25 strains of Acinetobacter baumannii,Pseudomonasaeruginosa and Stenotrophomonas maltophilia were isolated,respectively.The resistance rate of Acinetobacter baumannii was high to 90%(exclude cefoperazone/sulbactam,18%).The resistance rate of Pseudomonas aeruginosa to trimethoprimsulfamethoxazole,cefotaxime,gentamycin,piperacillin were about 80%.The isolating rate of Stenotrophomonas maltophilia was low.The drug resistant rate to ciprofloxacin,cefoperazone/sulbactam,trimethoprimsulfamethoxazole was less than 35% and to cefotaxime,aztreonam,piperacillin was more than 80%.The isolating rate of multidrug resistant strains showed an increasing tendency,58.54% strains were drug resistant to 5 kind antibiotics in 2009.Conclusion The drugresistance status of three nosocomial gram negative bacilli was serious,the selection of antibiotics should base on the drug susceptibility results医.学.全.在.线www.lindalemus.com.

Key words:Nosocomial infections;Nonfermentation gram negative bacilli;Multidrug resistance

非发酵糖革兰阴性杆菌引起的医院感染及其多重耐药性日益严重,特别是对亚胺培南耐药的鲍曼不动杆菌、铜绿假单胞菌等所致的严重感染已成为临床抗感染治疗难点之一。因此监测非发酵糖革兰阴性杆菌感染及其耐药性变化趋势,对于有效预防和治疗不动杆菌感染有重要意义。本研究回顾性分析了我院3种非发酵糖革兰阴性杆菌对抗菌药物的耐药状况,旨在指导临床科学用药。


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