脑梗死患者治疗后短期内病变区域形态改变缓慢,其临床征状、体征有改善时, CT扫描影像学上不一定有变化,而SPECT显像可观察到不同程度的变化[1-2]。应用SPECT对术前,术后的循环代谢变化观察有助于评价手术的疗效。近年来,有学者用SPECT显像观察药物、针刺、体外反搏等对rCBF影响[3-9]。据报道,吻合术后患者临床症状得以改善[10-12]。研究表明SPECT脑显影与常用评价疗效的Barthel指数呈正相关。本组患者治疗前SPECT脑灌注显像均有不同程度的放射性缺损,治疗后伴随临床症状的改善,多数缺损区消失或缩小;图像改变与临床所见基本平行,均支持上述观点。本研究结果间接支持部分学者的观点,认为颈内动脉闭塞或高度狭窄所致的脑缺血实施颅内外动脉吻合术可改善临床症状,改善局部脑血流量,预防完全性卒中的发生。本组病例数较少,随访时间较短,但作者认为缺血性脑血管病治疗前后SPECT脑灌注显像可直观显示血流及代谢的改变,从而反映治疗效果,可以客观、灵敏地为临床疗效评价提供客观的参考依据医.学全.在.线网站www.lindalemus.com。
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