综上所述, O3气浴对难治性糖尿病足安全性高,疗效显著,保肢率高,值得临床应用。
【参考文献】
[1] Apelqvist J,Bakker K, van Houtum WH,et al.International consensus and practical guidelines on the management and the prevention of the diabetic foot.International Working Group on the Diabetes Foot[J]. Diabetes Metab Res Rev, 2000,16(suppl1):84-92.
[2] 李仕明.糖尿病足与相关并发症的诊治[M].北京:人民卫生出版社,2003:474-475.
[3] 咸玉欣,侯为开,陈 丽. 糖尿病足的临床特点及诱发因素[J]. 山东医药, 2005, 45(7): 36-37.
[4] Menabde GT, Natroshvili ND, Natroshvili TD. Ozonotherapy for the treatment of parodontitis[J]. Georgian Med News,2006(134):43-46医.学.全.在.线www.lindalemus.com.
[5] Parkhisenko IuA, Glukhov AA. Use of ozone therapy and hydropressure technologies in complex intensive therapy of surgical sepsis[J].Khirurgiia(Mosk), 2001(4):55-56.
[6] Larini A, Bocci V. Effects of ozone on isolated peripheral blood mononuclear cells[J]. Toxicol In Vitro, 2005, 19(1): 55-61.
[7] AlDalain SM,Martínez G, Candelario J, et al. Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats [J]. Pharmacol Res, 2001,44(5):391-396.
[8] Hanley AJ, Festa A,D′Agostino RB Jr,et al.Metabolic and inflammation variable clusters and prediction of type 2 diabetes: factor analysis using directly measured insulin sensitivity[J]. Diabetes,2004,53(7):773-781.
[9] TafilKlawe M,Wozniak A,Drewa T,et al.Ozone therapy and the activity of selected lysosomal enzymes in blood serum of patients with lower limb ischaemia associated with obliterative atheromatosis [J].Med Sci Monit, 2002,8(7):520-525.