The emerging field of nutrigenetics and nutrigenomics is rapidly gaining importance, and this new international journal has been established to meet the needs of the investigators for a high-quality platform for their research. Endorsed by the recently founded ‘International Society of Nutrigenetics/Nutrigenomics' (ISNN), the ‘Journal of Nutrigenetics and Nutrigenomics’ welcomes contributions not only investigating the role of genetic variation in response to diet and that of nutrients in the regulation of gene expression, but is also open for articles covering all aspects of gene-environment interactions in the determination of health and disease. Original papers and reviews cover the genetic basis for the variable responses to diet and lifestyle factors in chronic conditions (e.g. cardiovascular disease, obesity, diabetes, cancer), methods to assess gene-environment interactions and other related relevant topics, with research drawing from both human and animal studies.