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您现在的位置: 医学全在线 > 考研院校 > 华东地区2 > 浙江大学医学院 > 院系导师 > 正文:浙大医学院肿瘤学范伟民教授简介
    

浙大大学医学院肿瘤学范伟民教授个人信息

更新时间:2012/5/10 医学考研论坛 在线题库 评论

学术期刊编委和稿件评审人:浙大科学 (Zhejiang University Science,China);实用肿瘤学 (Practical Oncology,China);国际肝胆胰疾病杂志 (HBPD International,China); Cancer Research (USA); Clinical Cancer research (USA);Molecular Cancer Therapeutics (USA); American Journal of Pathology (USA);Biochemical Pharmacology (USA);Carcinogenesis (UK);Journal of Histochemistry & Cytochemistry (USA);Journal of Biological Chemistry (USA);Oncogene (UK);International Journal of Cancer (Germany);Oncology Research (USA);International Journal of Hematology (Japan);Cancer Letter (UK);British Pharmacology (UK);Molecular Pharmacology (USA);Journal of Pharmacy and Pharmacology (Germany);BMC Cancer (UK);Oncogene(Germany),NanoToday (SG);Cell Death and Differentiation (UK);等等。

代表性论文(Selected from 70):
1. Fan, W,.Kasahara, M., Gutknecht, J., Klein, D., Jonkers, J., and Klein J. Shared class II MHC polymorphisms between human and chimpanzees. Human Immunol. 26:107-121, 1989
2.Fan, W., Trifilette, R. Cooper T. and Norris, J.S. Cloning of a µ class glutathione S-transferase gene and identification of the glucocorticoid regulatory domains in its 5’flanking region. Proc. Natl. Acad. Sci. U.S.A. 89:6104-6108, 1992
3. Fan, W., Cooper, T. and Norris, JS. Characterization of selective glucocorticoid dependent responses in a glucocorticoid resistant smooth muscle tumor cell line. J. Cell. Physiol. 156:88-95, 1993
4. Johnson, KR., Wang, L., Miller, MC., Willingham, MC. Fan, W. 5-Flurouracil interferes with paclitaxel cytotoxicity against human solid tumor cells. Clin. Cancer Res. 3:1739-1745, 1997
5. Fan, W., Ma, JX. And Norris, JS. Molecular cloning of TA16, a transcription repressor, that may mediate glucocorticoid-induced growth arrest of leiomyosarcoma cells, Mol. Endocrin. 11:1342-1352, 1997
6. Fan, W., Kou, H., Shen, D. and LeRoy, EC. Identification of altered expression of ADT/ATP translocase and laminin during cellular senescence in vitro. Exp. Geront. 33:457-465, 1998www.lindalemus.com
7. Johnson, R.K., Young, KK, and Fan, W. Antagonistic interplay between anti-mitotic and G1/S arresting agents in experimental combination therapy. Clin. Cancer Res. 5:2559-2565, 1999
8. Fan, W. Possible mechanisms of paclitaxel-induced apoptosis, Biochem. Pharmacol, 57:1215-1221, 1999
9. Miller, CM., Johnson, KR., Willingham, MC. and Fan, W. Apoptotic cell death induced by baccatin III, a precursor of paclitaxel, occurs without G2/M arrest. Caner Chemother & Pharmacol. 44:444-452, 1999
10.Huang, Y. Johnson RK, Norris, JS. and Fan, W. Nuclear factor-kappaB/I-kB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells. Cancer Res. 60:4426-4432, 2000
11.Zeng, S., Chen, YZ, Johnson, KR. and Fan, W. In vitro evaluation of sequential-dependent combination between docetaxel and doxorubicin in human tumor cells. Clin. Cancer Res. 6:3766-3773, 2000
12.Huang, Y. and Fan, W. IkB kinase activation is involved in the regulation of paclitaxel-induced apoptosis in solid tumor cells. Mol. Pharmacol. 61:105-113, 2002
13. Sui, M., Dziadyk, J., Zhu, XM, and Fan, W. Cell cycle dependent antagonistic interactions between paclitaxel and -radiation in combination therapy. Clin. Cancer Res. 10:4848-4857, 2004
14.Fan, W. Sui, M. and Huang, Y. Glucocorticoids inhibit taxane-induced apoptosis: Mechanisms and clinical impact. Curr. Med. Chem. 11:403-411, 2004www.lindalemus.com
15.Huang, Y. Fang, Y. Wu, J., Dziadyk, J., Zhu, XM, Sui, M., and Fan, W. Regulation of vinca alkaloid-induced apoptosis by NF-kappaB/IkB pathway in human tumor cells. Mol. Cancer Therap. 3: 271-277, 2004.
16.Sui, M. and Fan, W. Combination of gamma-radiation antagonizes the cytotoxic effects of vincristine and vinblastine on both mitotic arrest ad apoptosis. Int. Radio. Oncol. Phy. Bio. 1151-1158, 2005
17. Sui, M. Xoing X, Kraft A. and Fan, W. Combination of gemcitabine antagonizes antitumor activity of paclitaxel through prevention of mitotic arrest and apoptosis. Cancer Biol. Ther. 5:1015-1021, 2006
18.Sui, M., Chen, F., Chen, Z. and Fan, W. Glucocorticoids interfere the therapeutic efficacy of paclitaxel against human breast and ovarian xenograft tumors. Int. J. Cancer. 119-712-717, 2006
19. Sui, M. Huang, Y., Park, BH, Davidson, NE., Fan, W. Estrogen receptor-alpha mediates breast cancer cells resistance to paclitaxel through inhibition of apoptotic cell death. Cancer Res. 67: 5337-5344, 2007.

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