二、2008年以来SCI论文
1. Qiaoyuan Yang, Zhigang Jie, Sheng Ye, Zhengrong Li, Zhiyuan Han, Jianjun Wu,Yuanqi Li, Chengfeng Yang, Yiguo Jiang(通讯作者). Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility. Oncogene. 2012 (revised). (SCI IF: 7.414)
2. Yiguo Jiang (通讯作者),Yan Wu, Anne R. Greenlee, Jianjun Wu, Zhiyuan Han, Xun Li,Yao Zhao. miR-106a-mediated malignant transformation of cells induced by anti- benzo[a]pyrene-trans-7,8-diol-9,10-epoxide. Toxicological Sciences. 2011;119(1): 50-60. (SCI IF: 5.093)
3. Qiaoyuan Yang, Zhigang Jie, Hong Cao, Anne R. Greenlee, Chengfeng Yang, Fei Zou,Yiguo Jiang(通讯作者). Low-level expression of let-7a in gastric cancer and its involvement in tumorigenesis by targeting RAB40C.
www.lindalemus.com Carcinogenesis. 2011;32(5):713-722. (SCI IF: 5.402)
4. Zhiyuan Han, Qiaoyuan Yang, Bingbing Liu, Jianjun Wu, Yuanqi Li,Chengfeng Yang, Yiguo Jiang(通讯作者). MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol. Carcinogenesis, 2012;33(1):131-139. (SCI IF: 5.402)
5. Zhishan Wang, Junling Yang, Theresa Fisher, Hua Xiao, Yiguo Jiang, Chengfeng Yang. Akt activation is responsible for enhanced migratory and invasive behavior of arsenic-transformed human bronchial epithelial cells. Environmental Health Perspectives. 2012;120(1):92-97.(SCI IF: 6.087)
6. Yong Zhao, Zhishan Wang, Yiguo Jiang, Chengfeng Yang. Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells. Cancer Letters. 2011;313:54-63.(SCI IF: 4.864)
7. Yao Zhao, Huanying Liu, Yuanqi Li, Jianjun Wu, Anne R. Greenlee, Chengfeng Yang, Yiguo Jiang(通讯作者). The role of miR-506 in transformed 16HBE cells induced by anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide. Toxicology Letters. 2011;205(3):320-326. (SCI IF: 3.581)
8. Linhua Liu, Yiguo Jiang (通讯作者), Hongyu Zhang, Anne R. Greenlee, Rian Yu, Qiaoyuan Yang. MiR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. Toxicology in Vitro. 2010;24(4):1168-1175. (SCI IF: 2.546)
9. Huihan Duan, Yiguo Jiang (通讯作者), Hongyu Zhang, Yan Wu. MiR-320 and miR-494 affect cell cycles of primary
www.lindalemus.com murine bronchial epithelial cells exposed to benzo(a)pyrene. Toxicology in Vitro. 2010;24(3):928-935. (SCI IF: 2.546)
10. Linhua Liu, Yiguo Jiang (通讯作者), Hongyu Zhang,Anne R.Greenlee, Zhiyuan Han. Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8- dihydrodiol-9,10-epoxide. Life Sciences. 2010;86(5-6):192-198. (SCI IF: 2.451)
11. Yiguo Jiang(通讯作者), Juan Fu, Anne R. Greenlee, Yuelan Shen, Huihan Duan and Xuemin Chen. Effects of silencing of HER2/neu gene in anti-BPDE-transformed cells. Toxicology in Vitro.2009;23(1):53-59. (SCI IF: 2.546)12. Yuelan Shen, Yiguo Jiang(通讯作者), Anne R.Greenlee, Lanlan Zhou and Linhua Liu. MicroRNA expression profiles and miR-10a target in anti-benzo[a]pyrene-7,8-diol-9,10- epoxide-transformed human 16HBE cells. Biomedical and Environmental Sciences.2009; 22(1):14-21. (SCI IF: 1.063)
13. Lanlan Zhou, Yiguo Jiang(通讯作者),Aijun Tan, Anne R Greenlee, Yuelan Shen, Linhua Liu and Qiaoyuan Yang. Silencing of N-Ras gene expression using shRNA decreases transformation efficiency and tumor growth in transformed cells induced by anti-BPDE. Toxicological Sciences.2008;105(2):286-294. (SCI IF: 5.093)
三、2008年以来科研成果与获奖论文(仅列第一完成人)
1. 2008年广东省科学技术成果奖二等奖,肺癌化学病因及其干预的实验研究,第一完成人。(本项目还获得广州市科学技术成果奖一等奖和中华预防医学会科学技术成果奖三等奖)
2. 2011年广东省优秀硕士学位论文,miR-106a和miR-17-5p在反式二羟环氧苯并芘诱导细胞恶变中的作用,研究生论文导师。
3. 2010年广东省优秀硕士学位论文
www.lindalemus.com,反式二羟环氧苯并芘诱导恶变细胞中miR-494和miR-22对PTEN基因调控及其功能研究,研究生论文导师。
4. 2009年(首届)广东省优秀硕士学位论文,RNA干扰技术研究N-Ras基因表达改变在人支气管上皮细胞恶变中的作用,研究生论文导师。
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