1.DraynaD,Jarnagin A,Mclean J,et al Colnning and sequencing of human cholesteryl estertransfer protein cDna,Narure,1987,327:632-634
2.AbbeyM.Savage J,Mackimnnon A,et al .Detection of lipid transfer protein activity inrabbit perfusate.Biochim Biophys Acta,1984,793:481-484
3.NishidaH,Katolt,Nishida T.Affinty of lipid transfer protein for lipid and lipoproteinparticles as infuenced by lecithine cholesteryl acyltransferase.J Biol Chem,1990,265:4876-4883
4.TallA.Plasma lipid transfer proteins .Jlipid Res ,1986<27:361-367
5.HussainM,Maxfield F,Mas Olira J,et al .Clearance of chylomicron remnants by the lowdenisty lipoprotein receptor-related.J Biol Chem,1991,266:13936-13940
6.ScottrupJenesen L Alpha-Macroglobulins:structure,shape and mechansim of proteinasecomplesx formation. J Biol Chem,1989,264:11536-11542
7.StricklandD,Ashcom J,Williams S,et al Sequence identity between the α2-Macroglobulinreceptor and low density lipoprotein receptor-related protein suggests thatthis molecule is a multifunctional receptor ,J Biol Chem,1990,265:17401-17404
8.BrownM,Goldstein J,et al .A receptor mediated pathway for cholesterol homeostasis.Science,1986,232:34-47.
9.SmithJ R,Oshrne T F,Goldstein J L,et al Identification of nucleotides responsiblefor enhancer activity of sterol regulatory element in LDLR gene.J BiolChem,1990,265:2306-2310
10.BriggsM R,Yokoyama C,Wang X,et al .Nuclear protein that binds sterol regulatoryelement of low density lipoprotein receptor promotor.j BiolChem,1990,265:14490-14496
11.Youkoyama C,Wang X,Bringgs M R,et al ,srebp-1,a basic-helix-loop-helix-leucinezipper proteins that controls transcription of the low density lipoproteinreceptor gene Cell,1993,75:187-197
12.GoldsteinJL ,Brown M S.Regulation of the mevalonate pathway .Natute,1990,343:425-430
13.RajavashiothT B,Taylor A.K,Andalibi A,et al .Identification of a zinc finger protein thatbinds to the sterol regulatory element .Science,1989,245:640-643
14.WangX,Briggs M R,Hus X,et al. Nuclear protein that binds sterol regulatory elementof low density lipoprotein receptor promoter.J.Biol .Chem,1993,268:14497-14504
15.Kadesch T,Consequences of heteromeric interactions among helix-loop-helixprotein.Cell Growth Differ.1993,4:49-55
16.BeckmanH,Sul K,kadesch T.TFE3:a helix-loop-helix protein that activated transcriptionthrough the immunoglobulin enhancer motif .Gene.KEV.1990,4:167-179
17.HuaX,Yokoyama C,WuJ,et al.SREBP-2,a second basic-helix-loop-helix-leucine zipperprotein that stimulates transcription by binding to a sterol regulatory elementProc Natl Acad Sci USA,1993,90:11603-11607
18.SatoR,Yang J,Wang X,et al.Assignment of the membrane attachment ,DNA bindings ,andtranscriptional activation domains of sterol regulatory element-bindingprotein-1(SREBP-1).J Biol Chem,1994,269:17267-17273
19.WangX,Sato R,Brown M S,et al SREBP-1,a membrane-bound transcription factor releasedby sterol-regulated proteolysis ,Cell,1994,77:53-62
20.MaPTS,Gil G,Sudhof T C,et al .Mevinolin,an inhibitor of cholesterol sythesisinduces Mrna for LDLDR in livers of hasmters and rabbits .Proc Natl Acad SciUSA,1986,83:8370-8374
21.MehrabianM,Callaway K A,Clarke C F,et al Regulation of rat liver 3-hydroxy-3-methsutarylcoenzyme A synthase and the chromosomol localization of the humen gene J BiolChem,1986,261:16249-16255
22.BrownM S,Goldstein J L.A receptor mediated pathway for cholesterol homeostasis.Science,1986,232:34-47
23.ShergZ,Otani H,Brown M S,et al.Independent regulation of sterol regulatoryelement-binding protein 1 and 2 in hasmster liver.Prot Natl Acad SciUSA,1995,92:935-938
24.StreicherR,Kotzka J,Muller-Wieland D,et al .SREBP-1mediates activation of the lowdensity lipoprotein receptor promoter by insulin and insulin-like growthfactor-I.J Biol Chem;1996,7128-7133
25.WetterauJ R,Zilversmit D B.Atriglyceride and cholesteryl ester transfer protein associatedwith liver microsomes .J,Biol Chem,1984,259(17):10863-10886
26.WetterauJ R,Aggerbect,L P,Laplud M L ,et al .Structural properties of the microsomaltriglyceride transfer rpotein complex.Biochemistry.1991,30(18):4406-4412
27.WetterauJ R,Combs K A.Snipnner S N,et al .Protein disulfide isomerase is a component ofthe microsomal triglyceride transfer protein complex.J BiolChem,1990,265(17):9800-9807
28.GoldbergerR F,Epstein C J,Acceleration of reactivation of reduced bovine pancreaticribonuclease by a microsomal system from rat Liver j Biol Chem,1963,238:628-635
29.SharpD,Ricci B Kicnzle B Kienzle B,et al Human microsomal triglyceride transferprotein large subunit gene structure, Biodomistry ,www.lindalemus.com/shiti/1994,33(31):9057-9061
30.SharpD,Blindeman L.Combs K A et al .Cloning and gene defects in microsomaltriglyceride transfer protein associated wiyth abetalipoproteinaemia Nature,1993,258:999-1001
31.MathurS N,Born E,Marygy S,et al .Microsomal triglyceride transfer protein in CaCo-2Cell:characterization and regulation .J Lipid Res,1997,38(1);61-67
32.Weterau J R,Aggerbert LP.Bouma ME ,et al Absence of microsomal triglycetridetransfer protein in individuals with abetalipoproteinaemiaScience,1992,258:999-1001
33.WetterauJ R,Combs K A,Mclean LR ,et al .Protein disulfide isomnerase appears necessaryto maintain the catalytically active structure of the microsomal triglyceridetransfer protein .Biochemistry,1991,30(40):9728-9735
34.RicciB,Shrp D.Rourke E,et al .A30-amino acid truncation of the microsomaltriglyceride transfer proteinlarge subunit disrupts its interaction withprotein disulfide-isomerase and causesabetalipoproteinaemia.J,Biol.Chem,1995,270(24):14281-14285
35.WetterauJ R,Lin M,Jamil H.Microsomal triglyceride transfer protein Biochim Biophy Acta,1997,1345(1);136-150
36.BorenJ,Rustaeus S,Olofsson S.O.Studies on the assembly of apolipprotein B-48containing verylow density lipoproteins in MCARH7777 cells,j BiolChem,1994,(269(41)25879-25888
37.AtaelA.Wetterau J R.Mechansim of microsomcl triglyceride transfer protein catalyzedlipid transport.Biochemistry,1993 ,32(39);10444-10450
38.SnidermanA,et al .Alseuce of microsomal triglyceride transfer protein in indevidualswith abetalipoproteinemia.
39.ShrpD,Blinderma L,Combs K,et al.Cloning and gene defects in microsomal triglyeridetransfer protein associated with abetalipoproteinemia Nature ,1993,365:65
40.SnidermanA S,Marpole D M,Sdinner B,Kwiviterovich ,et al.The saaociaton of coronaryatherosclerosis cholesterol content in human plasma low density lipoprotein.Prot Nat Acad Sci USA,1990,97:604-608
41.SnidermanA S,Marpole D M.Skinner B,Kwivterovich ,et al.The association of coronaryatherosclerosis cholesterol content in human plasma low density lipoprtein.Prot Natl Acad Sci USR ,1990,97:604-608
42.TengB,Thompson GR,Smiderman AD,et al.Composition and distrbution of low densitylipoprotein fracteons in hyperapobetalipoproteinemia ,normolipidemia andfamilial hypercholesteroemia Prot Natl Acad Sci USa ,1983,80:6662-6666
43.KwiterovichPo Jr,white S,Forte T,et al.Hyperapobetalipoproteinemia in a kinderd withfamilial combined hyperlipidemica and familial hypercholeserolemia .ArterosclerThromb,1987,7:211-225
44.KwiterovichPo Jr,Coresh J Bachorik PL Prevalence of hyperapobetalipopproteinemia and otherlipoprotein phenotypes in men(≤50years )and women(≤60years)with coronarydisease Am J Cardiol,1993,71:631-639
45.BrunzdllJD.Sniderman AD,Albers JJ,et al.Apolipoprotein b and coronary artery disease inhumans.Arterioscler Thromb,1984,4:79-83
46.Kwiterovichpo Jr.HyperAopB:a pleiotrothic phenotype characterized by dense low densityliporoteins and associated with coronary artery disease.ClinChem,1988:34(supple B-1-B-135)B71-B83
47.CianfloneK,Kwiterovich po Jr,Wslsh M,et al.Stimulation of fatty acid uptake andtriglyceride synthesis in human cultured sdin fibroblasts and adipocytes by aserum protein.Biohys Res commun,1987,144:94-100
48.CianfloneKM,Rodriguez MA,Welsh MJ,et al.Effect of acylation-stimulation protein ontriglyceride synthesis in cultured skin fibroblasts from normals and patientswith hyperapobetalipoproteinemia(Abstract)Arteriosclerosis,1987,7:496
49.CianfloneKM,Rodriguez MA,Walsh M,et al.Purification and characterization ofcaylation-stmulating protein,J Biol Chem,1987,7:496
50.KwiterovichPo Jr,Motevlli M,Miller M Acylation stimulating activity inhyperapobetalipoproteinemia fibrolasts enhanced cholesterol esterification withanother serum basic protein BPⅡ.Proc Natl Acad Sci USA,1990,87:8980-8994
51.VahounyGV,chanderbhan R,kharroabi A.Sterol carrier and lipid transfer protein(Revicw).Adv Lipid Res,1987,22:83-113
52.KwiterovichPO,Jr,Motevalli M,Miller M.The effect of three serum basic proteins on the massof lipids in normal and hyperAopB fibroblasts Arterioscler Thromb,1994,14:1-7
53.TengBA,Forse MA,Rodriguez AD,et al.Adipose tissue glyceride synthesis in patientseith hyper aplbetalipoprotenemia J Physiol Pharmacol,1988,66:239-242
54.CianfloneKM,Maslowska MH.Sniderman AD.Impaired response of fibroblasts from patientswith hyperapobeta lipoproteinemia to acylation-stimulating protein.JclinInvest.,1990,85:722-30
55.BabirakSP.Iverius PH,Fujimoto WY.Detection and characterization of the hetwww.lindalemus.com/jianyan/eroazygousstate for lipoprtein lipase deficiency ,Arteriosclenosis .1989,9:326-34
56.KwiterovichPO.Jr,Motevalli M,Miller M,The effect of three serum basic proteins on the massof lipid in normal and hyperapoB fibroblasts .Arterioscler Thromb,1994,141-7
57.Baldo AD.Sniderman S Kohen MK,Cianflone signal transduction pathway ofacylation stimulating protein involvement of protein kinase C.J lipid Res1995,36:1415-1426
58.KwiterovichPO Jr ,Motevalli Miller M,Inhibition of protein tyrosine dinase alters theeffcet of serum basic protein I on tracylglycerol and cholesterol differentlyin normal and hyperapoB fibroblasts Arteriolcler Thromb VascBiol,1995,15:1195-1203
59.CastagnaMY,Takai KK,et al .Direct activation of calcium activated phospholipiddependent protein dinase by tumor promoting phorbol esters J BiolChem,1982,257:7847-7851
60.WittersL A,and PJ,Blackshear,Protein kinase C mediated phosphorylation in intact cellsMethods Enzymol1987,141:412-425
61.EtscheidBG,Albert KA,Villereal ML,et al.Transduction of the bradykinin response inhuman fibroblasts prolonged elevation of diacyglycerol level and itscorrelation cell.Reg .1991,3:229-239
62.ZorVE,Her T,Harell G.et al.Arachidonic acid release bybasophilic leudemia cellsand macrophages stimulated by Ca2+ionophores,antigen anddiacylglycerol:essential role for protein dinase C and preventionbyglucocorticosteroids.Biochem Biophys Acta.1990,1091:385-392
63.IshizudaTJ,Hoffman DR,Cooper JE,et al.Clucose induced synthesis of ciacylglycerol denovo is associated with translocation cactivation of protein kinase C in ratadipocytes FEBS Lett.1989,249:234-238
64.SatoR.Goldstein JL,Browm MS,Replacement of serine871 of hamster3-hydroxy-3methylglutaryl coA reductase prevents phosphorylation by aAMP-activated kinase and blocks inhibition of sterol synthesis indrced by ATpdepletion Proc Natl Acad Sci USA,1993,90:9261-9265
65.BolenJB,Non erceptor tyrosine protein kinases Oncogene.1993,8:2025-2031
66.ParkDJ.Nin HK,Rhee SG,IgE-in duced tyrosine phosphorylation of phospholipase Cr-1in rat basophilic leukemia cells J.Biol Chem,1991,266:24237-24240
67.CianfloneK,AD Sniderman M.J.Walsh.H.et al.Purification and characterization of acylationstimulating protein .J.Biol Chem,1989,264:426-430
68.GerminarioR,A Sniderman D Manuels S.et al .Coordinate response of triacylglycerolsynthesis and glucose transport by acylation stimulating protein ,Metab ClinExp.1993,42:574-580
69.YasruelZ,Cianflinge K,Sniderman AD,et al.Effect of caylation stimulating protein onthe triacylglycerol synthetic pathway of human adipose tissue .Lipids.1991,26:495-499
70.MayorekNo,I Grinstein and J.Bar Tana.Triacylglycerol .synthesis in cultured rathepatocytes EurJ Biochem,1989,182:395-400
71.TengB.Sniderman AD.Soutar AK,et al. Metabolic basis of hyperapobetalipoproteinemiaJ Clin Invest .1986,77:663-672
72.CookKS,Min D,Fnhnson et al.Adipsin:a circulating serine protease homolog secretedby adipose tissue and sciatic nerve.Science(Wash.DC).1987,237:402-405
73.WhiteRT.Damon .N,Hancodk ,et al.Human adipoin is identical to complement factor Dand is expressed at high levels in adipose tissue.J BiolChem,1992,267:9210-9213
74.ChoyLN,Rosen BS.B.M Spiegelman.Adipsln and an endogenous pathway of complement fromadipose cells,J Biol Chem,1992,267:12736-12741
75.CianfloneKA,Snielerman D.Walsh MJ,et al .Adipsin/Acylatin stimulating protein system inhuman adipocytes :regulation of triacylglycerolsynthesis.Bioxhemistry.1994,33:9489-9495
76.SpiegelmanBM,Fraik M,Green,H,Molecular cloning of mRNa from 3T3 adipocytes J BiolChem,258,16:10083-10089
77.CookKS,Groves ,DL,Min HY,et al.A devlopmently regulated mRNA from 3T3 adipo cytescncodes A novel serine protease homologue .Proc Natl Acad SciUSA.1985,82:6480-6484
78.SnidermanA.Shapiros ,Marpole D,et al. Association of coronary atheroscleros is with Ahperapo beta lipoprotenemia .Proc Natl Acad Sci USA,1980,97:604-608
79.SnidermanA.Wolfson V,Teng B.Association of hyperaobetalipwproteinemia with endogenoushypertrglyceridemia and atherosclerosis Bachorikp Ann Intern Med.1982,97:833-839
80.TengB Thompson GR Sniderman AD,Composition and distrbution of low ednsity lipoproteinfractions in hyperapobetalipoproteinemia normolpidemia ,and familialhypercholesterolemia .Proc Natl Acad Sci USa 1983,80:6662-6666
81.Flier JS,Cook KS,Vsher P,et al.Severely Iimpaired adipsin expression in geneticand acquired obesity ,Science .1987,244:1483-1487
82.RosenBS,Cook KS,Yaglom Jet al .Adipsin and Comlement factor D activity:animmune-pelated defect in obesity .Science ,1989,244:1483-1487
83.DovisRA,Boogaerts JR.Intranepatic assembly of very low density lipoproteins J Biolchem,1982,257:10908-10913
84.HugliTE.Biochemistry and biology of anaphylatoxin curr topics microbiol immunol,1989,153:181-208
85.PrazF.Rauth EJ.Growth-supporting activity of fragment ba of the human alternativecomplement pathway for activated murine B lymphocytes .J Exp Med1986,163,1349-1354
86.AmbrusJL,Jr Peters MG,Fauci AS,et al.The ba fragment of xomplement factor B Inhibitshuman Blymphocyte proliferation J Immunol .1990,144:1549-1533
87.CampeauL Enjabert M.lesperange J et al .The pelation of risk factors to thedevelopment of atheroscerosis in saphenous-vein bypass corafts and theprogression of disease in the native circulation N Engl J Med.1984,311:1329-1332
88.BrownBO,Alberts JJ,Fisher LD,et al.Regression of coronary artery disease as a resultof intensive lipid-lowering therapy in men with high levels of apolipoproteinB.N Engl J Med,1990,319:1289-1298
89.KwiterovichPO,Ir.whitxy ,Forte Tet al.Hyperapobetalipoproteinemia in a dindred withfamilial combined hyperlipidemia and rfmilial hypercholesterolemiaArtriosclerosis,1987,7:211-225
90.SandkampM,Funke H.Schulte H,K liporotein (a)Is An Iadependent risk tactor formyocardial in farction at Yong are ,Clin Chem,1990,36:20-6
91.ladiasJA,K witerovich PO,Ir,Smith H,et al.A missense mutation arinine 4019-tryptophanin apolipoprotein B in a famliy with hyperapob and premature atherosclerosis.Arteriosclersis ,1987,7:492
92.GavishD,Brinton EA,Breslow JL,Heritable allele –specisic differences in amounts ofapoB,and low-density lipoproteins in plasma.Science.1989,244:72-76
93.CoreshJ,Kwiterovich PO,Jr,Antoaradis SE,HyperapoB a pleiotropic phenotypecheracterized by dende lowdendity lipoproteins and associated with coronarydiseade .Am J Hum Genet ,1990,47(3):A130
94.TengB.Sniderman AD,Krauss RM,Modulation of apolipoprotein B antigenic determinantsin human low density lipoprtein subclasses J Biol chem,1985,260;5067-5072
95.KnighyBL,Thompson GR,Soutar AK.Binding and degradation of heavy and lighysubfractions of low density lipoprotein by cultured fibroblasts and macrophagesAtherosclerosis.1986,59:301-306.
96.WhiteR T, Damm D.Hanxock N.et al. Cell Biol.1991 in press.
